Knowledge Center

Patent / Jan 01, 1976

16.beta.-Methyl-17-hydroxypregna-1,4,9(11)-triene-3,20-dione

Authors:
Source:
GB 1397267

The title compd. I was prepd. from pregnanetrione II. Thus, ketalization of II using HOCH2CH2OH followed by redn. using KBH4 and then dehydration gave pregnene III. The Grignard reaction of III and MeMgBr followed by acid hydrolysis and bromination-dehydrobromination gave I.

Also in the Knowledge Center

Related Content

Formulation

We develop inhalation & nasal products with our partners following Quality by Design principles to reach optimal product performance through robust processes.

Page
Read more

Manufacturing

Hovione has extensive manufacturing capacity in Particle Engineering providing the right scale and flexibility for all our customers.

Page
Read more

Epidel™

Epidel™ is an innovative technology with the ability to deliver sustained-release pharmaceuticals via surface erosion resulting in the ability to precisely tune pharmacokinetics to meet the target indication needs.

Page
Read more