Google Chrome
Safari
Firefox
Edge
Knowledge Center
Patent / Jan 01, 1976
16.beta.-Methyl-17-hydroxypregna-1,4,9(11)-triene-3,20-dione
Source:
GB 1397267
The title compd. I was prepd. from pregnanetrione II. Thus, ketalization of II using HOCH2CH2OH followed by redn. using KBH4 and then dehydration gave pregnene III. The Grignard reaction of III and MeMgBr followed by acid hydrolysis and bromination-dehydrobromination gave I.
Also in the Knowledge Center
/ Apr 15, 2021
Laser diffraction as a powerful tool for amorphous solid dispersion screening and dissolution understanding
Read more
Scientific Article
/ Mar 09, 2021
Process Development of a Sonogashira Cross-Coupling Reaction as the Key Step of Tirasemtiv Synthesis Using Design of Experiments
Read more
Scientific Article
Scientific Article