Knowledge Center
Patent / Nov 08, 2014
Preparation of a tetracycline topical formulations
Source:
US 20140147504
The invention relates to a topical suspension formulation that includes a tetracycline, a liq. medium and a polymeric gelling agent. The tetracycline may be in the form of its salts, hydrates, or polymorphs and is in a suspended form within the formulation. The liq. medium is selected such that it does not completely dissolve or minimally dissolves the tetracycline. The gelling agent is a polymeric hydrocarbon gelling agent. Preferably, the tetracycline has a particle size of ≤20 μ. A formulation contained minocycline free base (cryst.) 1, mineral oil 30, and Versagel-M750 69%.
Also in the Knowledge Center
Scientific Article
/ Jan 01, 2003
Vitro characterization of jet-milled and in-situ-micronized fluticasone-17-propionate
Read more
Scientific Article
/ Jan 01, 1991
Structure of [RhH2(PPh3)2(bipy)]Cl (bipy = 2,2'-bipyridyl) from multinuclear NMR studies
Read more
Scientific Article