Knowledge Center

Patent / Jan 01, 1973

Catalytic dehalogenation, alone or with simultaneous reduction, of 11a-halo-6-deoxy-6-demethyl, 6-methylenetetracyclines by hydrazine

Authors:
  • Ivan Villax
Source:
GB 1360006

Methacycline and .alpha.- and .beta.-doxycycline sulfosalicylates were prepd. by dehalogenating 11a-chloro-6-deoxy-6-demethyl-6-methylene-5-hydroxytetracycline hydrofluoride or p-toluenesulfonate with N2H4.H2O-Pd-C and treating with 5-sulfosalicylic acid.

Also in the Knowledge Center

Related Content

Inhalation devices

Hovione’s inhalers offer our business partners access to simple, multipurpose, easy to use, globally competitive alternatives for inhalation delivery devices.

Page
Read more

GMP Certificates

GMP Certificates

Page
Read more

Nanoparticles

At Hovione we have both top-down and bottom-up technologies to produce pharmaceutical nanoparticles for oral delivery.

Page
Read more