Knowledge Center

Patent / Jan 01, 1973

16.beta.-Methyl-17.alpha.-hydroxypregna-1,4,9(11)-triene-3,20-dione and analogs

Authors:

Ivan Villax

Source:

GB 1397267

Pregnatrienedione I was prepd. from epoxypregnanetrione II in 7 steps. Thus, II underwent ketalization with HOCH2CH2OH, KBH4 redn., dehydration, Grignard reaction with MeMgBr, and deketalization to give pregnenedione III. III was treated with Br2-HOAc and then debrominated to I.

Also in the Knowledge Center

/ Dec 28, 2016

Electrophilic reagents for monohalomethylation, their preparation and their uses

Scientific Article

View

/ Dec 28, 2016

Continuous production of particles, micro- and/or nanoparticles, particulate amorphous solid dispersions, particulate co-crystals and pharmaceutical compns.

Scientific Article

View

/ Oct 23, 2016

Dry-Powder Inhalation Formulation: Balancing Performance and Manufacturability

Scientific Article

View

Browser not supported

Knowledge Center

16.beta.-Methyl-17.alpha.-hydroxypregna-1,4,9(11)-triene-3,20-dione and analogs

Also in the Knowledge Center

Electrophilic reagents for monohalomethylation, their preparation and their uses

Continuous production of particles, micro- and/or nanoparticles, particulate amorphous solid dispersions, particulate co-crystals and pharmaceutical compns.

Dry-Powder Inhalation Formulation: Balancing Performance and Manufacturability

Related Content

Our Experts

Speak Up!

Continuous Flow