Knowledge Center

Presentation / Oct 17, 2021

Understanding Dry Powder Inhalers Formulations: Role of Surface Polarity of lactose mixtures

Authors:
  • Ricardo Gonçalves
Source:
AAPS 2021

Track: Formulation and Delivery – Chemical
Rapid Fire: Role of Excipients in Formulation & Drug Product Development (CE)

 

Ricardo Gonçalves R&D Analytical Development | Hovione

 

 

Presenting Author: Ricardo Gonçalves - Analytical Scientist, R&D Analytical Development

 

Why do we use small lactose particles to improve Dry Powder Inhaler formulations? Why sieved and milled lactose particles present different properties? This presentation explores the role of surface energetics, measured using inverse gas chromatography, in the behavior of DPI formulations and the implication on their aerodynamic performance.

 

 

More details on PharmSci360

 

Also in the Knowledge Center

Related Content

ASD-HIPROS

ASD-HIPROS, Hovione’s Intelligent Proprietary Screening, is the most advanced and accurate tool to identify Amorphous Solid Dispersion formulations by Spray Drying with maximum performance and stability.

Page
Read more

Inspections History

Hovione sites are periodically inspected by the local and external authorities. All sites are FDA approved and with exception of New Jersey site all have EU GMP certificates.

Page
Read more

Dry Powder Inhalation formulation development

Hovione has considerable inhalation experience that allows us to implement strategies including conventional carrier based, neat (drug-alone) or composite particle formulations.

Page
Read more