Knowledge Center
Poster / Apr 20, 2016
Production of nano-solid dispersions using a novel co-precipitation process – benchmarking the in vivo performance with spray dried dispersions
Source:
10th PBP World Meeting
The use of amorphous solid dispersions (ASDs) to overcome the current solubility/bioavailability challenge of the new chemical compounds is gaining momentum. According to the recent DCS system, drugs belonging to BCS Class II (low solubility/high permeability) were sub-divided into two classes: Class IIa where molecules show dissolution-rate limited absorption, and the Class IIb where molecules present solubilitylimited absorption...
Also in the Knowledge Center
/ Apr 15, 2021
Laser diffraction as a powerful tool for amorphous solid dispersion screening and dissolution understanding
Read more
Scientific Article
/ Mar 09, 2021
Process Development of a Sonogashira Cross-Coupling Reaction as the Key Step of Tirasemtiv Synthesis Using Design of Experiments
Read more
Scientific Article
Scientific Article