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Patent / Jan 01, 1966

Tetracycline process

Authors:

Ivan Villax

Source:

BE 658387

A newly isolated strain of Streptomyces lusitanus var tetracyclini NCIB 9500 produces tetracycline with no co-production of chlortetracycline in the presence of Cl-. Thus, in a 6000-1. fermentor, with corn-steep medium contg. 1.5 g. NH4Cl/l. the strain produces 11.1 g. tetracycline/l. and no detectable amt. of chlortetracycline.

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Knowledge Center

Tetracycline process

Also in the Knowledge Center

Photostability studies of drug substances and products

A hybrid approach to reach stringent low genotoxic impurity contents in active pharmaceutical ingredients: Combining molecularly imprinted polymers and organic solvent nanofiltration for removal of 1,3-diisopropylurea

Pharmacokinetics, protein binding, and metabolic profile of 3H-icometasone enbutate following intravenous, oral, and intratracheal administrations to Sprague-Dawley rats

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