Knowledge Center

Patent / Jan 01, 1984

Rhodium-containing catalysts and their application

Authors:
  • Philip Page
Source:
EP 86046

A catalyst for hydrogenating tetracycline intermediates was prepd. by treating a Rh phosphine complex with a hydrazine. Thus (Ph3P)3RhCl was treated with N2H4 to give a catalyst contg. 16.95% Rh which was used together with PPh3 to hydrogenate I (RR1 = CH2) to give I (R = Me, R1 = H) free from epimer.

Also in the Knowledge Center

Related Content

Hot melt extrusion

Hot melt extrusion is a fast growing technology platform thas is utilized to solve difficult formulation challenges, primarily in the area of solubilization.

Page
Read more

Dry Powder Inhalation formulation development

Hovione has considerable inhalation experience that allows us to implement strategies including conventional carrier based, neat (drug-alone) or composite particle formulations.

Page
Read more

Financial Stability

Hovione is a well established and financially stable company

Page
Read more