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Patent / Jan 01, 2011

Process for the preparation of amorphous minocycline

Authors:

William Heggie
Zita Mendes
Rafael Antunes

Source:

PT 105199

A process was disclosed for the prepn. of the therapeutically useful anthracycline antibiotic minocycline (I) in amorphous and cryst. forms that are free of impurities, such as 4-epi-minocycline.

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Knowledge Center

Process for the preparation of amorphous minocycline

Also in the Knowledge Center

A method of preparing amorphous solid dispersion in submicron range by co-precipitation

Green production of cocrystals using a new solvent-free approach by spray congealing

Production of nano-solid dispersions using a novel co-precipitation process – benchmarking the in vivo performance with spray dried dispersions

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