Knowledge Center

Patent / Jan 01, 1977

Polyphosphate complexes of 6-demethyl-6-deoxy-6-methylenetetracycline and its 11a-halo derivatives

Authors:
  • Ivan Villax
Source:
ES 420504

5-Hydroxytetracycline 6,12-hemiacetal 12-phosphite was dehydrated by P2O5 to give 6-deoxy-6-demethyl-6-methylene-5-hydroxytetracycline polymetaphosphate. Similarly prepd. was 11a-chloro-6-deoxy-6-demethyl-6-methylene-5-hydroxytetracycline metaphosphate.

Also in the Knowledge Center

Related Content

Formulation

We develop inhalation & nasal products with our partners following Quality by Design principles to reach optimal product performance through robust processes.

Page
Read more

History of Hovione

Hovione was established in Portugal in 1959 by Ivan Villax with his wife, Diane Villax, and two other Hungarian refugees: Nicholas de Horthy and Andrew Onody, thus forming the name HOVIONE.

Page
Read more

Drug Product Manufacturing

To extend Hovione further we are now able to offer clinical supplies manufacturing for drug products.

Page
Read more