Knowledge Center

Patent / Jan 01, 1972

Polymetaphosphate complexes of .alpha.-6-deoxy-5-hydroxy tetracyclines

Authors:
  • Ivan Villax
Source:
DE 2152476

The title Na phosphate complexes, useful as antibiotics and more sol. in water than the corresponding acid complexes, were prepd. by reaction of the tetracycline with Na hexametaphosphate or HPO3 then NaOH in an inert org. solvent, e.g., DMF, EtOH, MeOH, or CHCl3.

Also in the Knowledge Center

Related Content

Corticosteroids

Corticosteroids are produced in two dedicated buildings on the Loures site, which are equipped with vessels ranging from 50L up to 4000L.

Page
Read more

Spray drying

Spray drying has become one of the most successful particle engineering technologies for improving drug bioavailability through the amorphous solid dispersion platform.

Page
Read more

Customers

Full transparency for your project anywhere at any time.

Page
Read more