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Patent / Jan 01, 2011

Methods and compounds for the preparation of monofluoromethylated biologically active organic compounds

Authors:

Emilia Leitao

Source:

WO 2011151625

Processes were disclosed for the prepn. of monofluoromethylated org. biol. active compds., such as fluticasone propionate and fluticasone furoate I [R = CH2Me, 2-furanyl, resp.], in the presence of fluorodecarboxylating reagents such as XeF2 and BrF3

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Knowledge Center

Methods and compounds for the preparation of monofluoromethylated biologically active organic compounds

Also in the Knowledge Center

Optimization of Supercritical CO2 Assisted Spray Drying for the Production of Inhalable Composite Particles

Breathing Simulators: One step closer to representative deposition profiles?

Paddle over disk as a dissolution test for orally inhaled drugs: discriminating composite from carrier-based formulations

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