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Patent / Jan 01, 2011

Methods and compounds for the preparation of monofluoromethylated biologically active organic compounds

Authors:

Emilia Leitao

Source:

WO 2011151625

Processes were disclosed for the prepn. of monofluoromethylated org. biol. active compds., such as fluticasone propionate and fluticasone furoate I [R = CH2Me, 2-furanyl, resp.], in the presence of fluorodecarboxylating reagents such as XeF2 and BrF3

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Knowledge Center

Methods and compounds for the preparation of monofluoromethylated biologically active organic compounds

Also in the Knowledge Center

Minocycline base polymorphic forms and its preparation method

Roller Compaction scale-up made simple: an approximate analytical solution to Johanson's rolling theory

Chalcones: Retrospective synthetic approaches and mechanistic aspects of a privileged scaffold

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