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Patent / Jan 09, 2014

Dynamic suspension drying to control Ostwald ripening

Authors:
  • Pedro Botas
  • David Goncalves
  • David Martins
  • Filipe Neves
  • Jose Melo
  • Nuno Almeida
Source:
WO 2014108687

The present invention relates to a process for the control of Ostwald Ripening phenomenon occurring in particle suspensions without the need for addn. of stabilizing agents, by using high pressure homogenization at mild conditions in a way that no increase or decrease in particle size occurs, thus allowing the stabilization of the suspension during the isolation step in the form of a dried powder.