Knowledge Center

Patent / Jan 01, 1973

Catalytic dehalogenation, alone or with simultaneous reduction, of 11a-halo-6-deoxy-6-demethyl, 6-methylenetetracyclines by hydrazine

Authors:
  • Ivan Villax
Source:
GB 1360006

Methacycline and .alpha.- and .beta.-doxycycline sulfosalicylates were prepd. by dehalogenating 11a-chloro-6-deoxy-6-demethyl-6-methylene-5-hydroxytetracycline hydrofluoride or p-toluenesulfonate with N2H4.H2O-Pd-C and treating with 5-sulfosalicylic acid.

Also in the Knowledge Center

Related Content

Hovione’s new Brand

In it for life

Page
Read more

The Hovione Experience - Lisbon

Welcome to Lisbon! Part of The Hovione Experience is ensuring your trip is unforgettable. Explore our suggestions for iconic attractions, exquisite cuisine, and get ready to feel the magic of this vibrant city.

Page
Read more

Continuous Flow

Expand the established chemistry space with Continuous Flow to deliver robust and sustainable processes.

Page
Read more