Knowledge Center

Patent / Jan 01, 1973

Catalytic dehalogenation, alone or with simultaneous reduction, of 11a-halo-6-deoxy-6-demethyl, 6-methylenetetracyclines by hydrazine

Authors:
  • Ivan Villax
Source:
GB 1360006

Methacycline and .alpha.- and .beta.-doxycycline sulfosalicylates were prepd. by dehalogenating 11a-chloro-6-deoxy-6-demethyl-6-methylene-5-hydroxytetracycline hydrofluoride or p-toluenesulfonate with N2H4.H2O-Pd-C and treating with 5-sulfosalicylic acid.

Also in the Knowledge Center

Related Content

History of Hovione

Hovione was established in Portugal in 1959 by Ivan Villax with his wife, Diane Villax, and two other Hungarian refugees: Nicholas de Horthy and Andrew Onody, thus forming the name HOVIONE.

Page
Read more

Global Sales and Marketing Meeting - GSM 2023

Hi there! Find here the relevant information about the Global Sales, Marketing & Communications and PMO Meeting in Lisbon, Portugal.

Page
Read more

The Hovione Experience - Lisbon

Welcome to Lisbon! Part of The Hovione Experience is ensuring your trip is unforgettable. Explore our suggestions for iconic attractions, exquisite cuisine, and get ready to feel the magic of this vibrant city.

Page
Read more