Knowledge Center

Patent / Jan 01, 1972

9-Fluoro-16.beta.-methyl steroids

Authors:
  • Ivan Villax
Source:
US 3792046

The title compds. (I) were prepd. from pregnatriene (II) by treatment with MeCONHBr and aq. HClO4 to give the 9.alpha.-bromo-11.beta.-hydroxy deriv., treatment with NaOH to give the 9,11-epoxy deriv. which was treated with aq. HF to give I (R = H) which could be treated with I-MeOH in the presence of CaO to give the 21-diiodo deriv. which was treated with KOAc, giving I (R = OAc).

Also in the Knowledge Center

Related Content

Devices

Hovione offers simple, patented and globally competitive dry powder inhalers – Disposable, Capsule, Blister and Large Dose DPIs – which are available for fully integrated turn-key development with formulation and for licensing.

Page
Read more

Global Sales and Marketing Meeting - GSM 2023

Hi there! Find here the relevant information about the Global Sales, Marketing & Communications and PMO Meeting in Lisbon, Portugal.

Page
Read more

Nanoparticles

At Hovione we have both top-down and bottom-up technologies to produce pharmaceutical nanoparticles for oral delivery.

Page
Read more