Knowledge Center

Patent / Jan 01, 1973

21-Sulfuric acid or 21-orthophosphoric acid ester sodium salts of prednisolone or 9.alpha.-fluoro-16.beta.-methylprednisolone

Authors:
  • Ivan Villax
Source:
DE 1793707

Prednisolone esters I [R = (HO)2PO, (HO)SO2; R1 = H, Me; R2 = H, F]. (4 compds.) were prepd. Thus, prednisolone (I; R = R1 = R2 = H) was treated with EtO2COCl-H3PO4 in Et3N-MeCN and then with NaOMe to give 66% I [R = (HO)2PO].

Also in the Knowledge Center

Related Content

Our Policies

Our Policies (Quality, HSEE, Human Resources, Innovation & Entrepreneurship) communicate and document our values.

Page
Read more

Analytical Support

Hovione has experience and capabilities to provide analytical services for Drug Substance, Drug Product and Inhalation Drug Product at all stages of development and commercial phases.

Page
Read more

The Hovione Experience - Cork

Welcome to Cork! Explore the city’s hidden gems and breathtaking scenery with us! Indulge in the Hovione Experience and immerse yourself in Irish culture.

Page
Read more