Knowledge Center
Patent / Jan 01, 1976
16.beta.-Methyl-17-hydroxypregna-1,4,9(11)-triene-3,20-dione
Source:
GB 1397267
The title compd. I was prepd. from pregnanetrione II. Thus, ketalization of II using HOCH2CH2OH followed by redn. using KBH4 and then dehydration gave pregnene III. The Grignard reaction of III and MeMgBr followed by acid hydrolysis and bromination-dehydrobromination gave I.
Also in the Knowledge Center
/ Jan 01, 1989
Rhodium-containing hydrogenation catalysts for the conversion of methacycline to doxycycline
Read more
Scientific Article
/ Jan 01, 1989
Rhodium hydrogenation catalysts particularly for stereoselective hydrogenation of methacycline to doxycycline
Read more
Scientific Article
/ Jan 01, 1989
Homogeneous catalytic system for hydrogenation of methylenetetracyclines and a process for the preparation of same
Read more
Scientific Article