Fine chemical companies add value through the characterization and control of the solid state

Fine chemical companies add value through the characterization and control of the solid state.

Although yield and purity have always been the first concerns of contractors manufacturing active pharmaceutical ingredients, a small but growing contingent is giving closer attention to issues such as particle size, crystal habit and polymorphism. These and other characteristics of the solid state have typically been left to formulators, but companies such as Hovione, SAFC, Pfanstiehl and Aptuit see an opportunity to add value and differentiate themselves.

Small features have large consequences